Complete your diagnosis at home with CeliacDx.
Just fill out our symptoms questionnaire and send us your cheek swab sample for celiac genetic testing along with any previous celiac disease test results. Our board certified pathologists will provide a comprehensive interpretation of your results and render a definitive diagnosis or recommend additional testing if more information is needed.
Celiac Diagnosis is Based on the Four Out of Five Rule
Symptoms
Genetics
tTG Antibodies
Biopsy
Gluten Free Diet
Diagnosing Celiac Disease
Four out of Five of the following criteria are used for a definitive celiac disease diagnosis:
1. Positive Celiac Symptoms (SX)
2. Positive Celiac Genetics
3. Positive tTg Antibodies (AB)
4. Positive Biopsy (BX)
5. Response To Gluten Free Diet (GFD)
Catassi and Fasano. The American Journal of Medicine (2010) 123, 691-693
Test with certainty knowing your CeliacDx report will give a definitive diagnosis. CeliacDx uses criteria recognized by experts to render a celiac disease diagnosis for every patient.
Most individuals with unresolved celiac disease diagnosis have previously had antibody and/or small bowel biopsy testing but no genetic testing.
CeliacDx uses genetic testing as a tie-breaker to render a definitive celiac disease diagnosis. Just fill out the symptoms questionnaire and send us any previous laboratory testing reports along with an at-home collected cheek sample. Our CeliacDx pathologists will do the rest!
The underlying cause of celiac disease is rooted in one’s genetic makeup. In fact celiac disease is the most common genetically based (and underdiagnosed) autoimmune disease in the United States. Without the presence of HLA-DQ2 and/or HLA-DQ8 celiac genes, an individual cannot develop the condition. However, having the relevant genes only indicates a susceptibility for developing celiac disease not a diagnosis. Definitive diagnosis is based on the four out of five rule which considers symptoms, diet, and test results to confirm the presence of celiac disease.
Use the four out of five rule
Four of five criteria below must be met for diagnosis
According to the celiac disease Foundation an accurate celiac disease diagnosis is delayed on average by 6 to 10 years. Delayed diagnosis often leads to worsening conditions. CeliacDx can help significantly reduce the time to diagnosis by combining the three tests into a Gold Standard Report designed to give a positive or negative diagnosis for every patient.
For a patient with celiac disease symptoms, positive family history, negative antibody test results and positive biopsy, use CeliacDx for resolution of positive versus negative celiac disease diagnosis.
Medical Advice Disclaimer:
CeliacDx provides test kits for the collection of genetic samples from patients in order to identify Celiac disease risk. None of the tests are meant to be a substitute for seeking professional medical advice, help, diagnosis, or treatment. The information on this website is for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment. Your use of the information on this website does not establish any patient-client relationship with any of the site’s creators. Users of this website assume the risk of acting upon any of the educational content that is provided.
